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A GuestI'm using this front gripshifter on a Giant Ranier with a Shimano Altus front der and SRAM X4 rear der. It's the first gripshifter I've tried, and I got it because I sprained my thumb badly and can't use a trigger shifter. This shifter downshifts well. However, it requires a LOT of effort to upshift and does not want to shift onto the highest gear in front if the chain is on anything but smallest 2-3 gears in back. I've had it adjusted at my LBS, but it's made no difference. Maybe the problem is caused by the derailleur combo, but when I ordered this grip shift, I had the understanding it would work regardless.